require(meta)
#** calculate OR and its SE
createORreference.fun=function(r,n)
{
logOR=c(0)
selogOR=c(NA)
for(i in 2:c(length(n)))
{
calculate=metabin(r[i],n[i],r[1],n[1],sm="OR")
logOR=c(logOR,calculate$TE)
selogOR=c(selogOR,calculate$seTE)
}
return(cbind(logOR=logOR,selogOR=selogOR))
}
# add OR and its SE to the dataset
add_var <- function(data=antidep){
data$studyid <- as.numeric(as.factor(data$studyid))
logORmat <- sapply(unique(data$studyid),function(i) createORreference.fun(data$r[data$studyid==i],data$n[data$studyid==i]),simplify = FALSE)
logORmat <- do.call(rbind,logORmat)
data$logOR <- c(logORmat[,1])
data$selogOR <- c(logORmat[,2])
data$cov <- data$selogOR^2
data
}
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